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Solubilization of Paclitaxel by Self-Assembled Amphiphilic Phospholipid-Mimetic Polymers with Varied Hydrophobicity

2-Methacryloyloxyethyl phosphorylcholine (MPC) polymers have been used as a coating agent on medical devices and as a carrier in drug delivery systems (DDSs). Paclitaxel (PTX) is a water-insoluble anticancer drug whose solubilizer is necessary for administration. Block and random copolymers composed...

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Detalles Bibliográficos
Autores principales: Kojima, Chie, Hirose, Tomoka, Katayama, Risa, Matsumoto, Akikazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8398084/
https://www.ncbi.nlm.nih.gov/pubmed/34451342
http://dx.doi.org/10.3390/polym13162805