Enhanced Bioavailability of AC1497, a Novel Anticancer Drug Candidate, via a Self-Nanoemulsifying Drug Delivery System

AC1497 is an effective dual inhibitor of malate dehydrogenase 1 and 2 targeting cancer metabolism. However, its poor aqueous solubility results in low bioavailability, limiting its clinical development. This study was conducted to develop an effective self-nanoemulsifying drug delivery system (SNEDD...

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Detalles Bibliográficos
Autores principales: Baral, Kshitis Chandra, Song, Jae-Geun, Lee, Sang Hoon, Bajracharya, Rajiv, Sreenivasulu, Godesi, Kim, Minkyoung, Lee, Kyeong, Han, Hyo-Kyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8398171/
https://www.ncbi.nlm.nih.gov/pubmed/34452103
http://dx.doi.org/10.3390/pharmaceutics13081142

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8398171/
https://www.ncbi.nlm.nih.gov/pubmed/34452103
http://dx.doi.org/10.3390/pharmaceutics13081142

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