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Enhanced Bioavailability of AC1497, a Novel Anticancer Drug Candidate, via a Self-Nanoemulsifying Drug Delivery System

AC1497 is an effective dual inhibitor of malate dehydrogenase 1 and 2 targeting cancer metabolism. However, its poor aqueous solubility results in low bioavailability, limiting its clinical development. This study was conducted to develop an effective self-nanoemulsifying drug delivery system (SNEDD...

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Detalles Bibliográficos
Autores principales:	Baral, Kshitis Chandra, Song, Jae-Geun, Lee, Sang Hoon, Bajracharya, Rajiv, Sreenivasulu, Godesi, Kim, Minkyoung, Lee, Kyeong, Han, Hyo-Kyung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8398171/ https://www.ncbi.nlm.nih.gov/pubmed/34452103 http://dx.doi.org/10.3390/pharmaceutics13081142

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