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Effective Perturbations of the Amplitude, Gating, and Hysteresis of I(K(DR)) Caused by PT-2385, an HIF-2α Inhibitor
PT-2385 is currently regarded as a potent and selective inhibitor of hypoxia-inducible factor-2α (HIF-2α), with potential antineoplastic activity. However, the membrane ion channels changed by this compound are obscure, although it is reasonable to assume that the compound might act on surface membr...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8398179/ https://www.ncbi.nlm.nih.gov/pubmed/34436399 http://dx.doi.org/10.3390/membranes11080636 |