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Effective Perturbations of the Amplitude, Gating, and Hysteresis of I(K(DR)) Caused by PT-2385, an HIF-2α Inhibitor

PT-2385 is currently regarded as a potent and selective inhibitor of hypoxia-inducible factor-2α (HIF-2α), with potential antineoplastic activity. However, the membrane ion channels changed by this compound are obscure, although it is reasonable to assume that the compound might act on surface membr...

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Detalles Bibliográficos
Autores principales: Hsiao, Hung-Tsung, Lu, Guan-Ling, Liu, Yen-Chin, Wu, Sheng-Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8398179/
https://www.ncbi.nlm.nih.gov/pubmed/34436399
http://dx.doi.org/10.3390/membranes11080636

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