Ataluren—Promising Therapeutic Premature Termination Codon Readthrough Frontrunner

Around 12% of hereditary disease-causing mutations are in-frame nonsense mutations. The expression of genes containing nonsense mutations potentially leads to the production of truncated proteins with residual or virtually no function. However, the translation of transcripts containing premature sto...

Descripción completa

Detalles Bibliográficos
Autor principal: Michorowska, Sylwia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8398184/
https://www.ncbi.nlm.nih.gov/pubmed/34451881
http://dx.doi.org/10.3390/ph14080785

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8398184/
https://www.ncbi.nlm.nih.gov/pubmed/34451881
http://dx.doi.org/10.3390/ph14080785

Ejemplares similares