Alpha-1 Antitrypsin Augmentation Inhibits Proteolysis of Neutrophil Membrane Voltage-Gated Proton Channel-1 in Alpha-1 Deficient Individuals

Background and Objectives: Alpha-1 antitrypsin is a serine protease inhibitor that demonstrates an array of immunomodulatory functions. Individuals with the genetic condition of alpha-1 antitrypsin deficiency (AATD) are at increased risk of early onset emphysematous lung disease. This lung disease i...

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Detalles Bibliográficos
Autores principales: Hawkins, Padraig, Sya, Julian, Hup, Nee Kee, Murphy, Mark P., McElvaney, Noel G., Reeves, Emer P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8398194/
https://www.ncbi.nlm.nih.gov/pubmed/34441020
http://dx.doi.org/10.3390/medicina57080814

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8398194/
https://www.ncbi.nlm.nih.gov/pubmed/34441020
http://dx.doi.org/10.3390/medicina57080814

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