Experimental Selection of Paromomycin Resistance in Leishmania donovani Amastigotes Induces Variable Genomic Polymorphisms

The relatively high post-treatment relapse rates of paromomycin (PMM) in visceral leishmaniasis treatment and the swift emergence of experimental drug resistance challenge its broad application and urge for rational use and monitoring of resistance. However, no causal molecular mechanisms to Leishma...

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Detalles Bibliográficos
Autores principales: Hendrickx, Sarah, Reis-Cunha, João Luís, Forrester, Sarah, Jeffares, Daniel C., Caljon, Guy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8398221/
https://www.ncbi.nlm.nih.gov/pubmed/34442625
http://dx.doi.org/10.3390/microorganisms9081546

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8398221/
https://www.ncbi.nlm.nih.gov/pubmed/34442625
http://dx.doi.org/10.3390/microorganisms9081546

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