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New Sulfanilamide Derivatives Incorporating Heterocyclic Carboxamide Moieties as Carbonic Anhydrase Inhibitors

Carbonic Anhydrases (CAs) are ubiquitous metalloenzymes involved in several disease conditions. There are 15 human CA (hCA) isoforms and their high homology represents a challenge for the discovery of potential drugs devoid of off-target side effects. For this reason, many synthetic and pharmacologi...

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Detalles Bibliográficos
Autores principales: Angeli, Andrea, Kartsev, Victor, Petrou, Anthi, Pinteala, Mariana, Vydzhak, Roman M., Panchishin, Svitlana Y., Brovarets, Volodymyr, De Luca, Viviana, Capasso, Clemente, Geronikaki, Athina, Supuran, Claudiu T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8398262/
https://www.ncbi.nlm.nih.gov/pubmed/34451924
http://dx.doi.org/10.3390/ph14080828