Sweat Chloride Testing and Nasal Potential Difference (NPD) Are Primary Outcome Parameters in Treatment with Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Modulators

With the advent of CFTR modulators, surrogate outcome parameters that accurately quantify the improvement in CFTR activity are needed. In vivo biomarkers that reflect CFTR ion transport and can serve as outcomes in the treatment of CFTR modulators are the sweat Cl(−) test (SCT), the nasal potential...

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Detalles Bibliográficos
Autores principales: Sermet-Gaudelus, Isabelle, Nguyen-Khoa, Thao, Hatton, Aurélie, Hayes, Kate, Pranke, Iwona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8398324/
https://www.ncbi.nlm.nih.gov/pubmed/34442373
http://dx.doi.org/10.3390/jpm11080729

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8398324/
https://www.ncbi.nlm.nih.gov/pubmed/34442373
http://dx.doi.org/10.3390/jpm11080729

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