Hyaluronic Acid Coating Reduces the Leakage of Melittin Encapsulated in Liposomes and Increases Targeted Delivery to Melanoma Cells

Melittin is a promising antitumor substance; however, it is a nonspecific cytolytic peptide, which limits its clinical application. In this study, melittin liposomes (Mel-Lip) and hyaluronic acid (HA)-modified Mel-Lip (Mel-HA-Lip) were designed to reduce the toxicity and increase the anti-tumor effe...

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Detalles Bibliográficos
Autores principales: Li, Yanyan, Ruan, Shuyao, Wang, Zhi, Feng, Nianping, Zhang, Yongtai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8398362/
https://www.ncbi.nlm.nih.gov/pubmed/34452196
http://dx.doi.org/10.3390/pharmaceutics13081235

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8398362/
https://www.ncbi.nlm.nih.gov/pubmed/34452196
http://dx.doi.org/10.3390/pharmaceutics13081235

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