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Effective Osteogenic Priming of Mesenchymal Stem Cells through LNA-ASOs-Mediated Sfrp1 Gene Silencing

Mesenchymal stem cell (MSC) transplantation has emerged as a promising approach for bone regeneration. Importantly, the beneficial effects of MSCs can be improved by modulating the expression levels of specific genes to stimulate MSC osteogenic differentiation. We have previously shown that Smurf1 s...

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Detalles Bibliográficos
Autores principales: García-Sánchez, Daniel, González-González, Alberto, García-García, Patricia, Reyes, Ricardo, Pérez-Núñez, María Isabel, Riancho, José A., Évora, Carmen, Rodríguez-Rey, José Carlos, Pérez-Campo, Flor M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8398380/
https://www.ncbi.nlm.nih.gov/pubmed/34452242
http://dx.doi.org/10.3390/pharmaceutics13081277