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LAG-3 Expression Predicts Outcome in Stage II Colon Cancer

Introduction: LAG-3 is an inhibitory immune checkpoint molecule that suppresses T cell activation and inflammatory cytokine secretion. T cell density in the tumor microenvironment of colon cancer plays an important role in the host’s immunosurveillance. We therefore hypothesized that LAG-3 expressio...

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Detalles Bibliográficos
Autores principales: Rhyner Agocs, Gaëlle, Assarzadegan, Naziheh, Kirsch, Richard, Dawson, Heather, Galván, José A., Lugli, Alessandro, Zlobec, Inti, Berger, Martin D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8398428/
https://www.ncbi.nlm.nih.gov/pubmed/34442393
http://dx.doi.org/10.3390/jpm11080749