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Inhibition of A549 Lung Cancer Cell Migration and Invasion by Ent-Caprolactin C via the Suppression of Transforming Growth Factor-β-Induced Epithelial—Mesenchymal Transition

The epithelial–mesenchymal transition (EMT) of cancer cells is a crucial process in cancer cell metastasis. An Aquimarina sp. MC085 extract was found to inhibit A549 human lung cancer cell invasion, and caprolactin C (1), a new natural product, α-amino-ε-caprolactam linked to 3-methyl butanoic acid,...

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Detalles Bibliográficos
Autores principales: Kim, So Young, Shin, Myoung-Sook, Kim, Geum Jin, Kwon, Hyukbean, Lee, Myong Jin, Han, Ah-Reum, Nam, Joo-Won, Jung, Chan-Hun, Kang, Ki Sung, Choi, Hyukjae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8398538/
https://www.ncbi.nlm.nih.gov/pubmed/34436304
http://dx.doi.org/10.3390/md19080465