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The GPR18 Agonist PSB-KD-107 Exerts Endothelium-Dependent Vasorelaxant Effects

GPR18 is an orphan GPCR that is activated by the cannabinoid tetrahydrocannabinol (THC). Emerging evidence indicates its involvement in the control of cardiovascular functions, including heart rate, contractility, vascular tone, as well as blood pressure. Therefore, we investigated the effects of se...

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Detalles Bibliográficos
Autores principales: Kotańska, Magdalena, Kubacka, Monika, Bednarski, Marek, Nicosia, Noemi, Szafarz, Małgorzata, Jawień, Wojciech, Müller, Christa E., Kieć-Kononowicz, Katarzyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8398562/
https://www.ncbi.nlm.nih.gov/pubmed/34451896
http://dx.doi.org/10.3390/ph14080799