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The GPR18 Agonist PSB-KD-107 Exerts Endothelium-Dependent Vasorelaxant Effects
GPR18 is an orphan GPCR that is activated by the cannabinoid tetrahydrocannabinol (THC). Emerging evidence indicates its involvement in the control of cardiovascular functions, including heart rate, contractility, vascular tone, as well as blood pressure. Therefore, we investigated the effects of se...
Autores principales: | Kotańska, Magdalena, Kubacka, Monika, Bednarski, Marek, Nicosia, Noemi, Szafarz, Małgorzata, Jawień, Wojciech, Müller, Christa E., Kieć-Kononowicz, Katarzyna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8398562/ https://www.ncbi.nlm.nih.gov/pubmed/34451896 http://dx.doi.org/10.3390/ph14080799 |
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