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Immunogenicity of Foot-and-Mouth Disease Virus Dendrimer Peptides: Need for a T-Cell Epitope and Ability to Elicit Heterotypic Responses

An approach based on a dendrimer display of B- and T-cell epitopes relevant for antibody induction has been shown to be effective as a foot-and-mouth disease (FMD) vaccine. B(2)T dendrimers combining two copies of the major FMD virus (FMDV) type O B-cell epitope (capsid proteinVP1 (140–158)) covalen...

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Detalles Bibliográficos
Autores principales: Cañas-Arranz, Rodrigo, de León, Patricia, Defaus, Sira, Torres, Elisa, Forner, Mar, Bustos, María J., Andreu, David, Blanco, Esther, Sobrino, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8398643/
https://www.ncbi.nlm.nih.gov/pubmed/34443302
http://dx.doi.org/10.3390/molecules26164714