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In Vitro-In Silico Tools for Streamlined Development of Acalabrutinib Amorphous Solid Dispersion Tablets

Amorphous solid dispersion (ASD) dosage forms can improve the oral bioavailability of poorly water-soluble drugs, enabling the commercialization of new chemical entities and improving the efficacy and patient compliance of existing drugs. However, the development of robust, high-performing ASD dosag...

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Detalles Bibliográficos
Autores principales: Mudie, Deanna M., Stewart, Aaron M., Rosales, Jesus A., Adam, Molly S., Morgen, Michael M., Vodak, David T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8398755/
https://www.ncbi.nlm.nih.gov/pubmed/34452217
http://dx.doi.org/10.3390/pharmaceutics13081257