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The Effects of pH and Excipients on Exenatide Stability in Solution

Exenatide, a glucagon-like peptide-1 receptor agonist, is the active pharmaceutical ingredient in Byetta(®) and Bydureon(®), two type 2 diabetes drug products that have generics and multiple follow-up formulations currently in development. Even though exenatide is known to be chemically and physical...

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Detalles Bibliográficos
Autores principales: Benet, Alexander, Halseth, Troy, Kang, Jukyung, Kim, April, Ackermann, Rose, Srinivasan, Santhanakrishnan, Schwendeman, Steven, Schwendeman, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8398870/
https://www.ncbi.nlm.nih.gov/pubmed/34452224
http://dx.doi.org/10.3390/pharmaceutics13081263