Determination of the Absolute Configuration of Bioactive Indole-Containing Pyrazino[2,1-b]quinazoline-3,6-diones and Study of Their In Vitro Metabolic Profile

In recent decades, fungi-derived naturally occurring quinazolines have emerged as potential drug candidates. Nevertheless, most studies are conducted for bioactivity assays, and little is known about their absorption, distribution, metabolism, and elimination (ADME) properties. To perform metabolic...

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Detalles Bibliográficos
Autores principales: Long, Solida, Furlani, Izadora L., de Oliveira, Juliana M., Resende, Diana I. S. P., Silva, Artur M. S., Gales, Luís, Pereira, José A., Kijjoa, Anake, Cass, Quezia B., Oliveira, Regina V., Sousa, Emília, Pinto, Madalena M. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8398919/
https://www.ncbi.nlm.nih.gov/pubmed/34443658
http://dx.doi.org/10.3390/molecules26165070

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8398919/
https://www.ncbi.nlm.nih.gov/pubmed/34443658
http://dx.doi.org/10.3390/molecules26165070

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