Potential Anti-Alzheimer Agents from Guanidinyl Tryptophan Derivatives with Activities of Membrane Adhesion and Conformational Transition Inhibitions

Guanidinyl tryptophan derivatives TGN1, TGN2, TGN3, and TGN4 were synthesized, and these compounds were shown to possess in vitro inhibitory activity for amyloid aggregation in a previous study. Nevertheless, the influence of the TGN series of compounds on the binding and permeation behaviors of an...

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Detalles Bibliográficos
Autores principales: Wongrattanakamon, Pathomwat, Jiaranaikulwanitch, Jutamas, Vajragupta, Opa, Jiranusornkul, Supat, Saenjum, Chalermpong, Yooin, Wipawadee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8398955/
https://www.ncbi.nlm.nih.gov/pubmed/34443456
http://dx.doi.org/10.3390/molecules26164863

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8398955/
https://www.ncbi.nlm.nih.gov/pubmed/34443456
http://dx.doi.org/10.3390/molecules26164863

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