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Dietary Soy Consumption and Cardiovascular Mortality among Chinese People with Type 2 Diabetes

Randomized controlled trials showed that soy intervention significantly improved blood lipids in people with diabetes. We sought to prospectively examine the association of soy consumption with the risk of cardiovascular death among individuals with diabetes. A total of 26,139 participants with a hi...

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Autores principales: Wang, Xiaowen, Lv, Jun, Yu, Canqing, Li, Liming, Hu, Yonghua, Qin, Li-Qiang, Dong, Jia-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8398979/
https://www.ncbi.nlm.nih.gov/pubmed/34444673
http://dx.doi.org/10.3390/nu13082513
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author Wang, Xiaowen
Lv, Jun
Yu, Canqing
Li, Liming
Hu, Yonghua
Qin, Li-Qiang
Dong, Jia-Yi
author_facet Wang, Xiaowen
Lv, Jun
Yu, Canqing
Li, Liming
Hu, Yonghua
Qin, Li-Qiang
Dong, Jia-Yi
author_sort Wang, Xiaowen
collection PubMed
description Randomized controlled trials showed that soy intervention significantly improved blood lipids in people with diabetes. We sought to prospectively examine the association of soy consumption with the risk of cardiovascular death among individuals with diabetes. A total of 26,139 participants with a history of diabetes were selected from the Chinese Kadoorie Biobank study. Soy food consumption was assessed by a food frequency questionnaire. Causes of death were coded by the 10th International Classification of Diseases. The Cox proportional hazard regression was used to compute the hazard ratios. During a median follow-up of 7.8 years, a total of 1626 deaths from cardiovascular disease (CVD) were recorded. Compared with individuals who never consumed soy foods, the multivariable-adjusted risks (95% confidence intervals) of CVD mortality were 0.92 (0.78, 1.09), 0.89 (0.75, 1.05), and 0.77 (0.62, 0.96) for those who consumed soy foods monthly, 1–3 days/week, and ≥4 days/week, respectively. For cause-specific cardiovascular mortality, significant inverse associations were observed for coronary heart disease and acute myocardial infarction. Higher soy food consumption was associated with a lower risk of cardiovascular death, especially death from coronary heart disease and acute myocardial infarction, in Chinese adults with diabetes.
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spelling pubmed-83989792021-08-29 Dietary Soy Consumption and Cardiovascular Mortality among Chinese People with Type 2 Diabetes Wang, Xiaowen Lv, Jun Yu, Canqing Li, Liming Hu, Yonghua Qin, Li-Qiang Dong, Jia-Yi Nutrients Article Randomized controlled trials showed that soy intervention significantly improved blood lipids in people with diabetes. We sought to prospectively examine the association of soy consumption with the risk of cardiovascular death among individuals with diabetes. A total of 26,139 participants with a history of diabetes were selected from the Chinese Kadoorie Biobank study. Soy food consumption was assessed by a food frequency questionnaire. Causes of death were coded by the 10th International Classification of Diseases. The Cox proportional hazard regression was used to compute the hazard ratios. During a median follow-up of 7.8 years, a total of 1626 deaths from cardiovascular disease (CVD) were recorded. Compared with individuals who never consumed soy foods, the multivariable-adjusted risks (95% confidence intervals) of CVD mortality were 0.92 (0.78, 1.09), 0.89 (0.75, 1.05), and 0.77 (0.62, 0.96) for those who consumed soy foods monthly, 1–3 days/week, and ≥4 days/week, respectively. For cause-specific cardiovascular mortality, significant inverse associations were observed for coronary heart disease and acute myocardial infarction. Higher soy food consumption was associated with a lower risk of cardiovascular death, especially death from coronary heart disease and acute myocardial infarction, in Chinese adults with diabetes. MDPI 2021-07-23 /pmc/articles/PMC8398979/ /pubmed/34444673 http://dx.doi.org/10.3390/nu13082513 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Wang, Xiaowen
Lv, Jun
Yu, Canqing
Li, Liming
Hu, Yonghua
Qin, Li-Qiang
Dong, Jia-Yi
Dietary Soy Consumption and Cardiovascular Mortality among Chinese People with Type 2 Diabetes
title Dietary Soy Consumption and Cardiovascular Mortality among Chinese People with Type 2 Diabetes
title_full Dietary Soy Consumption and Cardiovascular Mortality among Chinese People with Type 2 Diabetes
title_fullStr Dietary Soy Consumption and Cardiovascular Mortality among Chinese People with Type 2 Diabetes
title_full_unstemmed Dietary Soy Consumption and Cardiovascular Mortality among Chinese People with Type 2 Diabetes
title_short Dietary Soy Consumption and Cardiovascular Mortality among Chinese People with Type 2 Diabetes
title_sort dietary soy consumption and cardiovascular mortality among chinese people with type 2 diabetes
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8398979/
https://www.ncbi.nlm.nih.gov/pubmed/34444673
http://dx.doi.org/10.3390/nu13082513
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