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AUF1 gene transfer increases exercise performance and improves skeletal muscle deficit in adult mice
Muscle function and mass begin declining in adults long before evidence of sarcopenia and include reduced mitochondrial function, although much remains to be characterized. We found that mRNA decay factor AU-rich mRNA binding factor 1 (AUF1), which stimulates myogenesis, is strongly reduced in skele...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8399044/ https://www.ncbi.nlm.nih.gov/pubmed/34485607 http://dx.doi.org/10.1016/j.omtm.2021.07.005 |