Supersaturation and Solubilization upon In Vitro Digestion of Fenofibrate Type I Lipid Formulations: Effect of Droplet Size, Surfactant Concentration and Lipid Type

Lipid-based formulations (LBF) enhance oral drug absorption by promoting drug solubilization and supersaturation. The aim of the study was to determine the effect of the lipid carrier type, drop size and surfactant concentration on the rate of fenofibrate release in a bicarbonate-based in vitro dige...

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Detalles Bibliográficos
Autores principales: Katev, Vladimir, Tsibranska-Gyoreva, Sonya, Vinarov, Zahari, Tcholakova, Slavka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8399075/
https://www.ncbi.nlm.nih.gov/pubmed/34452248
http://dx.doi.org/10.3390/pharmaceutics13081287

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8399075/
https://www.ncbi.nlm.nih.gov/pubmed/34452248
http://dx.doi.org/10.3390/pharmaceutics13081287

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