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Supersaturation and Solubilization upon In Vitro Digestion of Fenofibrate Type I Lipid Formulations: Effect of Droplet Size, Surfactant Concentration and Lipid Type
Lipid-based formulations (LBF) enhance oral drug absorption by promoting drug solubilization and supersaturation. The aim of the study was to determine the effect of the lipid carrier type, drop size and surfactant concentration on the rate of fenofibrate release in a bicarbonate-based in vitro dige...
Autores principales: | Katev, Vladimir, Tsibranska-Gyoreva, Sonya, Vinarov, Zahari, Tcholakova, Slavka |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8399075/ https://www.ncbi.nlm.nih.gov/pubmed/34452248 http://dx.doi.org/10.3390/pharmaceutics13081287 |
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