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Secreted matrix metalloproteinase-14 is a predictor for antifibrotic effect of IC-2-engineered mesenchymal stem cell sheets on liver fibrosis in mice

INTRODUCTION: Transplantation of IC-2-engineered bone marrow-derived mesenchymal stem cell (BM-MSC) sheets (IC-2 sheets) was previously reported to potentially reduce liver fibrosis. METHODS: This study prepared IC-2-engineered cell sheets from multiple lots of BM-MSCs and examined the therapeutic e...

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Detalles Bibliográficos
Autores principales: Fukushima, Kenji, Itaba, Noriko, Kono, Yohei, Okazaki, Shizuma, Enokida, Shinpei, Kuranobu, Naomi, Murakami, Jun, Enokida, Makoto, Nagashima, Hideki, Kanzaki, Susumu, Namba, Noriyuki, Shiota, Goshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society for Regenerative Medicine 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8399086/
https://www.ncbi.nlm.nih.gov/pubmed/34504910
http://dx.doi.org/10.1016/j.reth.2021.08.004