DoE-Based Design of a Simple but Efficient Preparation Method for a Non-Effervescent Gastro-Retentive Floating Tablet Containing Metformin HCl

A sustained-release non-effervescent floating matrix tablet was prepared using a simple and efficient direct compression of spray-dried granules containing metformin hydrochloride and cetyl alcohol with hydroxypropyl methylcellulose K15M (HPMC K15M). The design of experiments was employed to explore...

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Detalles Bibliográficos
Autores principales: Kim, Byungsuk, Byun, Youngjoo, Lee, Eun Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8399106/
https://www.ncbi.nlm.nih.gov/pubmed/34452186
http://dx.doi.org/10.3390/pharmaceutics13081225

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8399106/
https://www.ncbi.nlm.nih.gov/pubmed/34452186
http://dx.doi.org/10.3390/pharmaceutics13081225

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