Iloprost Attenuates Oxidative Stress-Dependent Activation of Collagen Synthesis Induced by Sera from Scleroderma Patients in Human Pulmonary Microvascular Endothelial Cells

Endothelial cell injury is an early event in systemic sclerosis (SSc) pathogenesis and several studies indicate oxidative stress as the trigger of SSc-associated vasculopathy. Here, we show that circulating factors present in sera of SSc patients increased reactive oxygen species (ROS) production an...

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Detalles Bibliográficos
Autores principales: Giordo, Roberta, Thuan, Duong Thi Bich, Posadino, Anna Maria, Cossu, Annalisa, Zinellu, Angelo, Erre, Gian Luca, Pintus, Gianfranco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8399120/
https://www.ncbi.nlm.nih.gov/pubmed/34443317
http://dx.doi.org/10.3390/molecules26164729

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8399120/
https://www.ncbi.nlm.nih.gov/pubmed/34443317
http://dx.doi.org/10.3390/molecules26164729

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