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Iloprost Attenuates Oxidative Stress-Dependent Activation of Collagen Synthesis Induced by Sera from Scleroderma Patients in Human Pulmonary Microvascular Endothelial Cells
Endothelial cell injury is an early event in systemic sclerosis (SSc) pathogenesis and several studies indicate oxidative stress as the trigger of SSc-associated vasculopathy. Here, we show that circulating factors present in sera of SSc patients increased reactive oxygen species (ROS) production an...
Autores principales: | Giordo, Roberta, Thuan, Duong Thi Bich, Posadino, Anna Maria, Cossu, Annalisa, Zinellu, Angelo, Erre, Gian Luca, Pintus, Gianfranco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8399120/ https://www.ncbi.nlm.nih.gov/pubmed/34443317 http://dx.doi.org/10.3390/molecules26164729 |
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