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Characterization of ACE Inhibitors and AT(1)R Antagonists with Regard to Their Effect on ACE2 Expression and Infection with SARS-CoV-2 Using a Caco-2 Cell Model

Blood-pressure-lowering drugs are proposed to foster SARS-CoV-2 infection by pharmacological upregulation of angiotensin-converting enzyme 2 (ACE2), the binding partner of the virus spike (S) protein, located on the surface of the host cells. Conversely, it is postulated that angiotensin–renin syste...

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Detalles Bibliográficos
Autores principales:	Reus, Philipp, Schneider, Ann-Kathrin, Ulshöfer, Thomas, Henke, Marina, Bojkova, Denisa, Cinatl, Jindrich, Ciesek, Sandra, Geisslinger, Gerd, Laux, Volker, Grättinger, Mira, Gribbon, Philip, Schiffmann, Susanne
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8399150/ https://www.ncbi.nlm.nih.gov/pubmed/34440554 http://dx.doi.org/10.3390/life11080810

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