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Pitavastatin Is a Highly Potent Inhibitor of T-Cell Proliferation

Repositioning of approved drugs is an alternative time- and cost-saving strategy to classical drug development. Statins are 3-hydroxy-3-methylglutaryl-CoA (HMG CoA) reductase inhibitors that are usually used as cholesterol-lowering medication, and they also exhibit anti-inflammatory effects. In the...

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Detalles Bibliográficos
Autores principales: Voss, Linda, Guttek, Karina, Reddig, Annika, Reinhold, Annegret, Voss, Martin, Simeoni, Luca, Schraven, Burkhart, Reinhold, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8399298/
https://www.ncbi.nlm.nih.gov/pubmed/34451823
http://dx.doi.org/10.3390/ph14080727