Co-Spray Drying of Paracetamol and Propyphenazone with Polymeric Binders for Enabling Compaction and Stability Improvement in a Combination Tablet

Paracetamol (PCT) and propyphenazone (PRP) are analgesic drugs that are often combined in a single dosage form for enhanced pharmacological action. In this work, PCT and PRP were co-spray dried separately with hydroxypropyl methylcellulose (HPMC) and hydroxypropyl cellulose (HPC) using drug suspensi...

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Detalles Bibliográficos
Autores principales: Partheniadis, Ioannis, Nikolakakis, Ioannis, Zacharis, Constantinos K., Kachrimanis, Kyriakos, Al-Zoubi, Nizar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8399363/
https://www.ncbi.nlm.nih.gov/pubmed/34452221
http://dx.doi.org/10.3390/pharmaceutics13081259

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8399363/
https://www.ncbi.nlm.nih.gov/pubmed/34452221
http://dx.doi.org/10.3390/pharmaceutics13081259

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