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Co-Spray Drying of Paracetamol and Propyphenazone with Polymeric Binders for Enabling Compaction and Stability Improvement in a Combination Tablet

Paracetamol (PCT) and propyphenazone (PRP) are analgesic drugs that are often combined in a single dosage form for enhanced pharmacological action. In this work, PCT and PRP were co-spray dried separately with hydroxypropyl methylcellulose (HPMC) and hydroxypropyl cellulose (HPC) using drug suspensi...

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Detalles Bibliográficos
Autores principales:	Partheniadis, Ioannis, Nikolakakis, Ioannis, Zacharis, Constantinos K., Kachrimanis, Kyriakos, Al-Zoubi, Nizar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8399363/ https://www.ncbi.nlm.nih.gov/pubmed/34452221 http://dx.doi.org/10.3390/pharmaceutics13081259

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