Model-Informed Repurposing of Medicines for SARS-CoV-2: Extrapolation of Antiviral Activity and Dose Rationale for Paediatric Patients

Repurposing of remdesivir and other drugs with potential antiviral activity has been the basis of numerous clinical trials aimed at SARS-CoV-2 infection in adults. However, expeditiously designed trials without careful consideration of dose rationale have often resulted in treatment failure and toxi...

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Detalles Bibliográficos
Autores principales: Romano, Federico, D’Agate, Salvatore, Della Pasqua, Oscar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8399437/
https://www.ncbi.nlm.nih.gov/pubmed/34452260
http://dx.doi.org/10.3390/pharmaceutics13081299

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8399437/
https://www.ncbi.nlm.nih.gov/pubmed/34452260
http://dx.doi.org/10.3390/pharmaceutics13081299

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