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Targeted Liposomes Encapsulating miR-603 Complexes Enhance Radiation Sensitivity of Patient-Derived Glioblastoma Stem-Like Cells

Despite potential for clinical efficacy, therapeutic delivery of microRNAs (miRNA) remains a major translational barrier. Here, we explore a strategy for miRNA delivery in the treatment of glioblastoma, the most common form of adult brain cancer, that involves complexation of miRNA with polyethyleni...

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Detalles Bibliográficos
Autores principales: Shabana, Ahmed M., Xu, Beibei, Schneiderman, Zachary, Ma, Jun, Chen, Clark C., Kokkoli, Efrosini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8399469/
https://www.ncbi.nlm.nih.gov/pubmed/34452076
http://dx.doi.org/10.3390/pharmaceutics13081115