Drug Screening, Oral Bioavailability and Regulatory Aspects: A Need for Human Organoids

The intestinal epithelium critically contributes to oral bioavailability of drugs by constituting an important site for drug absorption and metabolism. In particular, intestinal epithelial cells (IEC) actively serve as gatekeepers of drug and nutrient availability. IECs’ transport processes and meta...

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Detalles Bibliográficos
Autores principales: Zietek, Tamara, Boomgaarden, Wolfgang A. D., Rath, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8399541/
https://www.ncbi.nlm.nih.gov/pubmed/34452240
http://dx.doi.org/10.3390/pharmaceutics13081280

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8399541/
https://www.ncbi.nlm.nih.gov/pubmed/34452240
http://dx.doi.org/10.3390/pharmaceutics13081280

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