Effects of the Autophagy-Inhibiting Agent Chloroquine on Acute Myeloid Leukemia Cells; Characterization of Patient Heterogeneity

Autophagy is a highly conserved cellular degradation process that prevents cell damage and promotes cell survival, and clinical efforts have exploited autophagy inhibition as a therapeutic strategy in cancer. Chloroquine is a well-known antimalarial agent that inhibits late-stage autophagy. We evalu...

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Detalles Bibliográficos
Autores principales: Grønningsæter, Ida Sofie, Reikvam, Håkon, Aasebø, Elise, Bartaula-Brevik, Sushma, Hernandez-Valladares, Maria, Selheim, Frode, Berven, Frode S., Tvedt, Tor Henrik, Bruserud, Øystein, Hatfield, Kimberley Joanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8399694/
https://www.ncbi.nlm.nih.gov/pubmed/34442423
http://dx.doi.org/10.3390/jpm11080779

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8399694/
https://www.ncbi.nlm.nih.gov/pubmed/34442423
http://dx.doi.org/10.3390/jpm11080779

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