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Modulation of the Mucosa-Associated Microbiome Linked to the PTPN2 Risk Gene in Patients with Primary Sclerosing Cholangitis and Ulcerative Colitis

Gut microbiota appears to be involved in the pathogenesis of primary sclerosing cholangitis (PSC). The protein tyrosine phosphatase nonreceptor 2 (PTPN2) gene risk variant rs1893217 is associated with gut dysbiosis in inflammatory bowel disease (IBD), and PTPN2 was mentioned as a possible risk gene...

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Detalles Bibliográficos
Autores principales: Denoth, Luisa, Juillerat, Pascal, Kremer, Andreas E., Rogler, Gerhard, Scharl, Michael, Yilmaz, Bahtiyar, Bluemel, Sena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8399714/
https://www.ncbi.nlm.nih.gov/pubmed/34442830
http://dx.doi.org/10.3390/microorganisms9081752