2-Hydroxypropyl-β-cyclodextrin Regulates the Epithelial to Mesenchymal Transition in Breast Cancer Cells by Modulating Cholesterol Homeostasis and Endoplasmic Reticulum Stress

Cholesterol metabolism affects endoplasmic reticulum (ER) stress and modulates epithelial-mesenchymal transition (EMT). Our previous study demonstrated that 2-hydroxypropyl-β-cyclodextrin (HP-β-CD) attenuated EMT by blocking the transforming growth factor (TGF)-β/Smad signaling pathway and activatin...

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Detalles Bibliográficos
Autores principales: Zhao, Yiyang, He, Linkang, Wang, Tian, Zhu, Lifang, Yan, Nianlong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8399758/
https://www.ncbi.nlm.nih.gov/pubmed/34436503
http://dx.doi.org/10.3390/metabo11080562

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8399758/
https://www.ncbi.nlm.nih.gov/pubmed/34436503
http://dx.doi.org/10.3390/metabo11080562

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