A first report of a rare TP53 variant associated with Li-Fraumeni syndrome manifesting as invasive breast cancer and malignant solitary fibrous tumor

BACKGROUND: Li-Fraumeni is a rare autosomal dominant cancer predisposition syndrome. The basis is a germline mutation of TP53 gene which encodes tumor suppressor protein resulting in early onset of tumors, most often breast cancer, soft tissue sarcomas, brain tumors, adrenocortical carcinomas, and l...

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Detalles Bibliográficos
Autores principales: Prejac, Juraj, Dedić Plavetić, Natalija, Gotovac Jerčić, Kristina, Borovečki, Fran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8399826/
https://www.ncbi.nlm.nih.gov/pubmed/34452612
http://dx.doi.org/10.1186/s12957-021-02370-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8399826/
https://www.ncbi.nlm.nih.gov/pubmed/34452612
http://dx.doi.org/10.1186/s12957-021-02370-8

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