Nanoparticulate Drug Delivery Strategies to Address Intestinal Cytochrome P450 CYP3A4 Metabolism towards Personalized Medicine

Drug dosing in clinical practice, which determines optimal efficacy, toxicity or ineffectiveness, is critical to patients’ outcomes. However, many orally administered therapeutic drugs are susceptible to biotransformation by a group of important oxidative enzymes, known as cytochrome P450s (CYPs). I...

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Detalles Bibliográficos
Autores principales: Zhang, Rui Xue, Dong, Ken, Wang, Zhigao, Miao, Ruimin, Lu, Weijia, Wu, Xiao Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8399842/
https://www.ncbi.nlm.nih.gov/pubmed/34452222
http://dx.doi.org/10.3390/pharmaceutics13081261

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8399842/
https://www.ncbi.nlm.nih.gov/pubmed/34452222
http://dx.doi.org/10.3390/pharmaceutics13081261

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