Design and Synthesis In Silico Drug-like Prediction and Pharmacological Evaluation of Cyclopolymethylenic Homologous of LASSBio-1514

Acylhydrazones are still an important framework to the design of new bioactive compounds. As treatment of chronic pain represents a clinical challenge, we decided to modify the structure of LASSBio-1514 (1), previously described as anti-inflammatory and analgesic prototype. Applying the homologation...

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Detalles Bibliográficos
Autores principales: Lima, Lidia Moreira, da Silva, Tiago Fernandes, da Silva Monteiro, Carlos Eduardo, Aparecida-Silva, Cristiane, Bispo Júnior, Walfrido, de Queiroz, Aline Cavalcanti, Alexandre-Moreira, Magna Suzana, Zapata-Sudo, Gisele, Barreiro, Eliezer J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8399892/
https://www.ncbi.nlm.nih.gov/pubmed/34443416
http://dx.doi.org/10.3390/molecules26164828

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8399892/
https://www.ncbi.nlm.nih.gov/pubmed/34443416
http://dx.doi.org/10.3390/molecules26164828

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