Evaluation of Ribavirin–Poloxamer Microparticles for Improved Intranasal Absorption

Ribavirin is a water-soluble antiviral compound which, owing to its inability to cross the blood–brain barrier, has limited effectiveness in treating viruses affecting the central nervous system. Direct nose-to-brain delivery was investigated for ribavirin in combination with poloxamer 188, an excip...

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Detalles Bibliográficos
Autores principales: Vasa, Dipy M., Bakri, Zainab, Donovan, Maureen D., O’Donnell, Lauren A., Wildfong, Peter L. D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8399989/
https://www.ncbi.nlm.nih.gov/pubmed/34452087
http://dx.doi.org/10.3390/pharmaceutics13081126

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8399989/
https://www.ncbi.nlm.nih.gov/pubmed/34452087
http://dx.doi.org/10.3390/pharmaceutics13081126

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