Cargando…
Evaluation of Ribavirin–Poloxamer Microparticles for Improved Intranasal Absorption
Ribavirin is a water-soluble antiviral compound which, owing to its inability to cross the blood–brain barrier, has limited effectiveness in treating viruses affecting the central nervous system. Direct nose-to-brain delivery was investigated for ribavirin in combination with poloxamer 188, an excip...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8399989/ https://www.ncbi.nlm.nih.gov/pubmed/34452087 http://dx.doi.org/10.3390/pharmaceutics13081126 |