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Lipoic Acid-Modified Oligoethyleneimine-Mediated miR-34a Delivery to Achieve the Anti-Tumor Efficacy

MiR-34a, an important tumor suppressor, has been demonstrated to possess great potential in tumor gene therapy. To achieve the upregulation of miR-34a expression level, an oligoethyleneimine (OEI) derivative was constructed and employed as the carrier through the modification with lipoic acid (LA),...

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Detalles Bibliográficos
Autores principales: Huang, Yu, Wang, Longxiang, Chen, Yingxuan, Han, Haobo, Li, Quanshun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8400101/
https://www.ncbi.nlm.nih.gov/pubmed/34443415
http://dx.doi.org/10.3390/molecules26164827