Sustained-Release Solid Dispersion of High-Melting-Point and Insoluble Resveratrol Prepared through Hot Melt Extrusion to Improve Its Solubility and Bioavailability

This study aimed to prepare a sustained-release solid dispersion of poorly water-soluble resveratrol (RES) with high melting point in a single hot melt extrusion step. A hydrophobic–hydrophilic polymeric blend (Eudragit RS and PEG6000) was used to control the release of RES. With the dispersive mixi...

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Detalles Bibliográficos
Autores principales: Zhu, Wenjing, Fan, Wenling, Zhang, Xiaotong, Gao, Meiqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8400122/
https://www.ncbi.nlm.nih.gov/pubmed/34443569
http://dx.doi.org/10.3390/molecules26164982

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8400122/
https://www.ncbi.nlm.nih.gov/pubmed/34443569
http://dx.doi.org/10.3390/molecules26164982

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