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Non-Covalent BTK Inhibitors—The New BTKids on the Block for B-Cell Malignancies
The B-cell receptor signalling pathway plays a critical role in development of B-cell malignancies, and the central role of Bruton’s tyrosine kinase (BTK) activation in this pathway provides compelling rationale for BTK inhibition as a therapeutic strategy for these conditions. Covalent BTK inhibito...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8400141/ https://www.ncbi.nlm.nih.gov/pubmed/34442408 http://dx.doi.org/10.3390/jpm11080764 |