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Non-Covalent BTK Inhibitors—The New BTKids on the Block for B-Cell Malignancies

The B-cell receptor signalling pathway plays a critical role in development of B-cell malignancies, and the central role of Bruton’s tyrosine kinase (BTK) activation in this pathway provides compelling rationale for BTK inhibition as a therapeutic strategy for these conditions. Covalent BTK inhibito...

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Detalles Bibliográficos
Autores principales: Lewis, Katharine L, Cheah, Chan Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8400141/
https://www.ncbi.nlm.nih.gov/pubmed/34442408
http://dx.doi.org/10.3390/jpm11080764