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MAP Kinase Pathways in Brain Endothelial Cells and Crosstalk with Pericytes and Astrocytes Mediate Contrast-Induced Blood–Brain Barrier Disruption

Neurointervention with contrast media (CM) has rapidly increased, but the impact of CM extravasation and the related side effects remain controversial. This study investigated the effect of CM on blood–brain barrier (BBB) integrity. We established in vitro BBB models using primary cultures of rat BB...

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Detalles Bibliográficos
Autores principales: Matsunaga, Yuki, Nakagawa, Shinsuke, Morofuji, Yoichi, Dohgu, Shinya, Watanabe, Daisuke, Horie, Nobutaka, Izumo, Tsuyoshi, Niwa, Masami, Walter, Fruzsina R., Santa-Maria, Ana Raquel, Deli, Maria A., Matsuo, Takayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8400240/
https://www.ncbi.nlm.nih.gov/pubmed/34452232
http://dx.doi.org/10.3390/pharmaceutics13081272