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Genetic Variants in PGE2 Receptors Modulate the Risk of Nephrosclerosis and Clinical Outcomes in These Patients

Prostaglandin E2 (PGE2) is a major actor mediating renal injury. We aimed to determine genetic variability in the genes coding for its receptors (PTGER1-4) and study associations with nephrosclerosis risk and clinical outcomes. We identified 96 tag-SNPs capturing global variability in PTGER1-4 and s...

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Detalles Bibliográficos
Autores principales: González, Luz María, Robles, Nicolás Roberto, Mota-Zamorano, Sonia, Valdivielso, José Manuel, López-Gómez, Juan, Gervasini, Guillermo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8400263/
https://www.ncbi.nlm.nih.gov/pubmed/34442416
http://dx.doi.org/10.3390/jpm11080772