Formulation Considerations for Autologous T Cell Drug Products

Genetically modified autologous T cells have become an established immunotherapy in the fight against cancer. The manufacture of chimeric antigen receptor (CAR) and αβ-T cell receptor (TCR) transduced T cells poses unique challenges, including the formulation, cryopreservation and fill–finish steps,...

Descripción completa

Detalles Bibliográficos
Autores principales: van der Walle, Christopher F., Godbert, Sonya, Saito, Gabriele, Azhari, Zein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8400304/
https://www.ncbi.nlm.nih.gov/pubmed/34452278
http://dx.doi.org/10.3390/pharmaceutics13081317

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8400304/
https://www.ncbi.nlm.nih.gov/pubmed/34452278
http://dx.doi.org/10.3390/pharmaceutics13081317

Ejemplares similares